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Coventry and Warwickshire Area Prescribing Committee
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 Formulary Chapter 4: Nervous system - Full Chapter
04.02.01  Expand sub section  Antipsychotic Drugs
04.02.01  Expand sub section  First-Generation Antipsychotic Drugs
04.02.01  Expand sub section  Second-Generation Antipsychotic Drugs
Amisulpride
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Formulary
Green SA

Treatment of acute and chronic psychoses


 Preferred-

 
Aripiprazole tablets
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Formulary
Green SA

Treatment of schizophrenia and episodes of mania 


 Preferred-

 
Link  NICE TA213: Aripiprazole for the treatment of schizophrenia in people aged 15 -17 years
Link  NICE TA292: Bipolar disorder (children) - aripiprazole
Olanzapine
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Formulary
Green SA

Treatment of acute and chronic psychoses, mania


Preferred-

 
Risperidone tablets
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Formulary
Green SA

Treatment of acute and chronic psychoses, mania 


Preferred-

 
Cariprazine Black Triangle
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Formulary
Green SI

Treatment of schizophrenia in adult patients


SecondLine- for primary care prescribing


 

 
Link  APC DPS097: Cariprazine - drug positioning statement
Lurasidone
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Formulary
Green SI

Treatment of schizophrenia


SecondLine-

 
Link  APC DPS057: Lurasidone - drug positioning statement
Quetiapine standard release tablets
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Formulary
Green SA

Treatment of schizophrenia and episodes of mania


Preferred-

 
Quetiapine XL
(Biquelle®)
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Formulary
Green SA

Treatment of schizophrenia and episodes of mania


Prescribe by cost effective brand


SecondLine-

 
Clozapine
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Formulary
Red SO

Treatment of resistant schizophrenia


Preferred-

 
Link  MHRA update: Clozapine and other antipsychotics: monitoring blood concentrations for toxicity - 08/20
Link  NICE QS80 section 4: Clozapine
 ....
 Non Formulary Items
Amisulpride liquid

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Non Formulary
Non Formulary
Aripiprazole liquid or orodispersible

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Non Formulary
Non Formulary
Clozapine liquid

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Non Formulary
Red SO

Treatment of resistant schizophrenia

Olanzapine orodispersible

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Non Formulary
Non Formulary
Paliperidone oral

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Non Formulary
Not Recommended
Treatment of schizophrenia and manic episodes
Risperidone liquid or orodispersible

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Non Formulary
Non Formulary
Sertindole
(Unlicensed)

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Non Formulary
Red SO

Treatment of schizophrenia


 

  
Key
note Notes
Section Title Section Title (top level)
Section Title Section Title (sub level)
First Choice Item First Choice item
Non Formulary Item Non Formulary section
Restricted Drug
Restricted Drug
Unlicensed Drug
Unlicensed
Track Changes
Display tracking information
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Blueteq
High Cost Drug Approval System

Traffic Light Status Information

Status Description

Preferred

Clinicians are free to prescribe these drugs. They are regarded as cost effective choices which have evidence to support their use.  

Second Line

These drugs should only be prescribed in the scenarios described in the formulary after preferred drug(s) have been ruled out.  

Non Formulary

Non-formulary choice - the vast majority of a patient’s needs should be met by use of formulary preferred choices and second line options when appropriate. Therefore the Clinician should only use a non-formulary drug if this can be justified and it is recommended that all such instances are recorded in the patient record.  

Green SA

Specialist Advised – Specialists may simply advise a patient’s GP to initiate these drugs themselves after they have made an initial assessment. Note: SA drugs can be initiated by the specialist according to patient need and also depending on local commissioning arrangements which may mandate, through the contract between provider and commissioner, that all SA drugs are treated as SI.  

Green SI

Specialist Initiation - These drugs must be initiated, i.e. the first dose prescribed, by the specialist and then may be continued when appropriate by the patient’s GP following communication from the specialist.  

Amber SC

Shared Care - Responsibility for prescribing may be transferred from secondary to primary care with the agreement of an individual GP and when agreed shared care arrangements have been established. The specialist MUST stabilize the patient before asking for care to be transferred. Only specialists should initiate these drugs. Prescribing should be transferred to GPs according to an Shared Care Agreement [SCA]   

Red SO

Specialist Only - These drugs are deemed to be not appropriate for prescribing by GPs. Specialists should not ask GPs to prescribe these drugs.   

Black BL

Black Listed Medicines - These drugs are considered inappropriate for prescribing in Coventry & Warwickshire as they are either not cost-effective or of proven benefit or both.   

Not Recommended

Not Recommended - These are drugs that are not recommended for use.  

Discontinued Medicines

Discontinued medicines - These are drugs that are no longer available to prescribe   

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